Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.5
USERS' SCORE
Good
Based on 10 Reviews
8.3
Supplement Facts
Serving Size: 2 VegCaps
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1,235 mg
1,372%
Quercetin
465 mg
*
Bromelain (Supplying 90 MCU)
50 mg
*
Top Medical Research Studies
9
We investigated whether quercetin, a natural plant compound, could help combat common cold caused by rhinovirus (RV). In our study, quercetin reduced RV replication and inflammation in airway cells both in laboratory settings and in mice. When given before or after infection, quercetin limited the virus's ability to replicate and decreased harmful immune responses.
While our findings are promising, indicating that quercetin acts at various points in the virus's lifecycle, we recognize the need for further research to solidify its effectiveness in treating or preventing common colds.
While our findings are promising, indicating that quercetin acts at various points in the virus's lifecycle, we recognize the need for further research to solidify its effectiveness in treating or preventing common colds.
Read More
8
We investigated how quercetin 7-glucoside (Q7G), sourced from Lagerstroemia speciosa, affects human rhinovirus 2 (HRV2), a leading cause of the common cold. Utilizing a method to reduce cytopathic effects, we found that Q7G significantly reduced HRV2 replication by blocking the virus's early infection stage.
Interestingly, compared to ribavirin, a known antiviral, Q7G showed stronger efficacy, suggesting its potential as a treatment for HRV2. While these results are promising, further research is needed to assess the practicality of using Q7G in common cold therapies.
Interestingly, compared to ribavirin, a known antiviral, Q7G showed stronger efficacy, suggesting its potential as a treatment for HRV2. While these results are promising, further research is needed to assess the practicality of using Q7G in common cold therapies.
Read More
8
We explored how vitamin C affects the severity of common colds through a comprehensive review of available studies. By including only randomized, placebo-controlled trials where participants received at least 1 gram of vitamin C daily, we aimed to investigate both the overall duration of colds and the intensity of symptoms experienced.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
Read More
Most Useful Reviews
9
Irreplaceable during cold
3 people found this helpful
This complex, featuring Vitamin C and Quercetin, is fantastic during a cold! It really helps me bounce back quickly.
Read More
9
Prevents seasonal colds
1 people found this helpful
This is an excellent ingredient for preventing colds, especially in the changing seasons. I give it to my children every two days while they're at school. Thanks to this, I've remained healthy and symptom-free!
Read More
9
Reduces colds
1 people found this helpful
This product is highly effective against nasal allergies. I've purchased it numerous times, and I've noticed that my children's allergies have improved, leading to a significant reduction in their colds and better sleep at night.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.5
- All Researches
9
We explored the role of flavonoid compounds, like quercetin, in reducing the frequency and severity of upper respiratory tract infections (URTIs) in healthy adults. An in-depth review of 14 studies showed that flavonoid supplementation notably reduced the incidence of URTIs by 33% and sick days by 40%.
However, we noted that changes in immune markers were minimal, indicating that while there are advantages in reducing infections, the immune response may not be significantly affected.
However, we noted that changes in immune markers were minimal, indicating that while there are advantages in reducing infections, the immune response may not be significantly affected.
Read More
9
We investigated whether quercetin, a natural plant compound, could help combat common cold caused by rhinovirus (RV). In our study, quercetin reduced RV replication and inflammation in airway cells both in laboratory settings and in mice. When given before or after infection, quercetin limited the virus's ability to replicate and decreased harmful immune responses.
While our findings are promising, indicating that quercetin acts at various points in the virus's lifecycle, we recognize the need for further research to solidify its effectiveness in treating or preventing common colds.
While our findings are promising, indicating that quercetin acts at various points in the virus's lifecycle, we recognize the need for further research to solidify its effectiveness in treating or preventing common colds.
Read More
9
We explored the potential benefits of vitamin C as a supplementary treatment for relieving common cold symptoms. By analyzing data from 10 randomized controlled trials, all focused on patients in China, we sought to understand how combining vitamin C with antiviral therapy might enhance recovery.
Our findings revealed that vitamin C supplementation could significantly improve overall efficacy, with a reported relative risk of 1.27. Moreover, it was shown to shorten the time it takes for symptoms to get better and for patients to heal, compared to antiviral therapy alone.
While vitamin C seems to have a positive impact when paired with antiviral drugs, it’s essential to note that its individual effects might not be fully clear due to the combined treatment approach used in the studies. Nonetheless, vitamin C presents itself as a promising addition to traditional cold treatments, helping patients manage their symptoms more effectively.
Our findings revealed that vitamin C supplementation could significantly improve overall efficacy, with a reported relative risk of 1.27. Moreover, it was shown to shorten the time it takes for symptoms to get better and for patients to heal, compared to antiviral therapy alone.
While vitamin C seems to have a positive impact when paired with antiviral drugs, it’s essential to note that its individual effects might not be fully clear due to the combined treatment approach used in the studies. Nonetheless, vitamin C presents itself as a promising addition to traditional cold treatments, helping patients manage their symptoms more effectively.
Read More
8
Quercetin's antiviral potential confirmed
We explored the effects of quercetin-3-methyl ether, a natural flavonoid, on the common cold virus, specifically human rhinovirus 1B (HRV1B).
In our study, we found that this compound not only inhibited the virus's replication in human cells but also targeted the early stages of infection.
Additionally, quercetin enhanced early cell death to help combat the virus's immune evasion tactics.
While our findings highlight its potential as a new antiviral agent, further research is necessary to confirm its effectiveness in broader treatments.
In our study, we found that this compound not only inhibited the virus's replication in human cells but also targeted the early stages of infection.
Additionally, quercetin enhanced early cell death to help combat the virus's immune evasion tactics.
While our findings highlight its potential as a new antiviral agent, further research is necessary to confirm its effectiveness in broader treatments.
Read More
8
Quercetin shows promise against viruses
We explored the effectiveness of quercetin-type flavonols in combating viral lower respiratory infections through a systematic review of 11 preclinical studies.
Our findings highlighted quercetin's impressive antiviral activity, showing lower mortality rates and reduced viral loads in infected animals.
Moreover, quercetin appeared to alleviate inflammation and mucus production, suggesting a multifaceted benefit for respiratory health. Overall, quercetin could be a promising option for those facing respiratory viral challenges.
Our findings highlighted quercetin's impressive antiviral activity, showing lower mortality rates and reduced viral loads in infected animals.
Moreover, quercetin appeared to alleviate inflammation and mucus production, suggesting a multifaceted benefit for respiratory health. Overall, quercetin could be a promising option for those facing respiratory viral challenges.
Read More
User Reviews
USERS' SCORE
Good
Based on 10 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Irreplaceable during cold
3 people found this helpful
This complex, featuring Vitamin C and Quercetin, is fantastic during a cold! It really helps me bounce back quickly.
Read More
9
Prevents seasonal colds
1 people found this helpful
This is an excellent ingredient for preventing colds, especially in the changing seasons. I give it to my children every two days while they're at school. Thanks to this, I've remained healthy and symptom-free!
Read More
9
Reduces colds
1 people found this helpful
This product is highly effective against nasal allergies. I've purchased it numerous times, and I've noticed that my children's allergies have improved, leading to a significant reduction in their colds and better sleep at night.
Read More
9
Effective for cough
3 people found this helpful
Excellent results! This is a fantastic complex for allergies and viral diseases. It helped alleviate a chronic cough. We also give it to our children at the onset of colds; it assists them in recovering more quickly.
Read More
7.5
Helps children recover
1 people found this helpful
My children struggled with frequent colds despite their best efforts. After exploring various medications, I opted for this dietary supplement, which arrived quickly. Although taken irregularly by my daughter, I've noticed improvements in their sinus issues; I believe it's down to the quercetin!
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Frequently Asked Questions
9
Sinus pain relief
2 people found this helpful
My forehead sinus pain, which started last October, persisted without any sniffles or flu. After taking one capsule twice daily for a week, my pain has disappeared entirely.
9
Effective for cough
3 people found this helpful
Excellent results! This is a fantastic complex for allergies and viral diseases. It helped alleviate a chronic cough. We also give it to our children at the onset of colds; it assists them in recovering more quickly.
9
Prevents seasonal colds
1 people found this helpful
This is an excellent ingredient for preventing colds, especially in the changing seasons. I give it to my children every two days while they're at school. Thanks to this, I've remained healthy and symptom-free!
9
Irreplaceable during cold
3 people found this helpful
This complex, featuring Vitamin C and Quercetin, is fantastic during a cold! It really helps me bounce back quickly.
7.5
Reduces nasal allergies
1 people found this helpful
My children tend to see a doctor monthly for their nose allergies, which makes catching a cold serious. A friend recommended this supplement, and thankfully, their nasal allergies have significantly diminished, improving their immunity.
8
Quercetin's antiviral potential confirmed
We explored the effects of quercetin-3-methyl ether, a natural flavonoid, on the common cold virus, specifically human rhinovirus 1B (HRV1B).
In our study, we found that this compound not only inhibited the virus's replication in human cells but also targeted the early stages of infection.
Additionally, quercetin enhanced early cell death to help combat the virus's immune evasion tactics.
While our findings highlight its potential as a new antiviral agent, further research is necessary to confirm its effectiveness in broader treatments.
In our study, we found that this compound not only inhibited the virus's replication in human cells but also targeted the early stages of infection.
Additionally, quercetin enhanced early cell death to help combat the virus's immune evasion tactics.
While our findings highlight its potential as a new antiviral agent, further research is necessary to confirm its effectiveness in broader treatments.
7
We investigated how quercetin affects the immune response to rhinovirus, which can cause the common cold. Our findings revealed that TLR2 plays a crucial role in regulating the body's initial immune response. In patients with chronic obstructive pulmonary disease (COPD), the TLR2 pathway functions differently, resulting in excessive inflammatory responses.
Notably, when we treated COPD airway cells with quercetin, we noticed a normalization of the immune response. This suggests that quercetin may help calm the immune system's overreaction to cold viruses by enhancing SIRT-1 expression. Overall, quercetin shows promise in regulating immune responses, especially in affected COPD cells.
Notably, when we treated COPD airway cells with quercetin, we noticed a normalization of the immune response. This suggests that quercetin may help calm the immune system's overreaction to cold viruses by enhancing SIRT-1 expression. Overall, quercetin shows promise in regulating immune responses, especially in affected COPD cells.
9
We explored the role of flavonoid compounds, like quercetin, in reducing the frequency and severity of upper respiratory tract infections (URTIs) in healthy adults. An in-depth review of 14 studies showed that flavonoid supplementation notably reduced the incidence of URTIs by 33% and sick days by 40%.
However, we noted that changes in immune markers were minimal, indicating that while there are advantages in reducing infections, the immune response may not be significantly affected.
However, we noted that changes in immune markers were minimal, indicating that while there are advantages in reducing infections, the immune response may not be significantly affected.
8
We explored how vitamin C affects the severity of common colds through a comprehensive review of available studies. By including only randomized, placebo-controlled trials where participants received at least 1 gram of vitamin C daily, we aimed to investigate both the overall duration of colds and the intensity of symptoms experienced.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
7
We explored the effects of vitamin C on common cold symptoms, particularly focusing on how it may assist in alleviating those pesky issues that come with viral respiratory infections. The research indicates that taking vitamin C, especially at the onset of symptoms, might help reduce the duration of discomfort, such as fever, chills, and chest pain.
Additionally, we noted that vitamin C could potentially reduce the severity of symptoms related to common cold-induced asthma and might decrease the need for hospital admissions in some cases. While the overall evidence about vitamin C's effectiveness isn’t exhaustive, oral consumption may provide relief for many experiencing early stages of viral infections.
However, we must emphasize that there is currently no strong evidence supporting the use of vitamin C specifically for preventing or treating COVID-19, which shares similar symptoms with typical respiratory infections. Therefore, while vitamin C appears beneficial for common cold symptoms, further high-quality research is essential to validate its efficacy and safety unequivocally.
Additionally, we noted that vitamin C could potentially reduce the severity of symptoms related to common cold-induced asthma and might decrease the need for hospital admissions in some cases. While the overall evidence about vitamin C's effectiveness isn’t exhaustive, oral consumption may provide relief for many experiencing early stages of viral infections.
However, we must emphasize that there is currently no strong evidence supporting the use of vitamin C specifically for preventing or treating COVID-19, which shares similar symptoms with typical respiratory infections. Therefore, while vitamin C appears beneficial for common cold symptoms, further high-quality research is essential to validate its efficacy and safety unequivocally.
8
We conducted an insightful study to explore whether vitamin C supplementation can help reduce the incidence of common colds among Republic of Korea Army recruits. Our research involved a rigorous randomised, placebo-controlled trial that included 1,444 soldiers over a 30-day period.
In this study, we divided the participants into two groups: one received a daily dose of 6,000 mg of vitamin C while the other received a placebo with no vitamin C. We investigated the soldiers' medical records to see how many of them contracted a cold during the training period.
Our findings showed encouraging results. The group that took vitamin C had a 20% lower risk of developing a common cold compared to those who took the placebo. Interestingly, this protective effect was especially pronounced among recruits in certain training camps, as well as never smokers and those who were physically ranked at level three.
Overall, we observed that vitamin C supplementation appears to be an effective strategy for reducing the incidence of common colds in military settings, which may lead to considerations for implementing vitamin C provisions during basic training for soldiers.
In this study, we divided the participants into two groups: one received a daily dose of 6,000 mg of vitamin C while the other received a placebo with no vitamin C. We investigated the soldiers' medical records to see how many of them contracted a cold during the training period.
Our findings showed encouraging results. The group that took vitamin C had a 20% lower risk of developing a common cold compared to those who took the placebo. Interestingly, this protective effect was especially pronounced among recruits in certain training camps, as well as never smokers and those who were physically ranked at level three.
Overall, we observed that vitamin C supplementation appears to be an effective strategy for reducing the incidence of common colds in military settings, which may lead to considerations for implementing vitamin C provisions during basic training for soldiers.
References
- Song JH, Mun SH, Mishra S, Kim SR, Yang H, et al. Quercetin-3-Methyl Ether Induces Early Apoptosis to Overcome HRV1B Immune Evasion, Suppress Viral Replication, and Mitigate Inflammatory Pathogenesis. Biomol Ther (Seoul). 2025;33:388. doi:10.4062/biomolther.2024.204
- Cho H, Kim S, Lee SH, Park Y. Effect of onion ( L.) peel extract on natural killer cell and cytokines in a randomized, double-blind, placebo-controlled trial. Nutr Res Pract. 2024;18:33. doi:10.4162/nrp.2024.18.1.33
- Brito JCM, Lima WG, Cordeiro LPB, da Cruz Nizer WS. Effectiveness of supplementation with quercetin-type flavonols for treatment of viral lower respiratory tract infections: Systematic review and meta-analysis of preclinical studies. Phytother Res. 2021;35:4930. doi:10.1002/ptr.7122
- Xander N, Reddy Vari H, Eskandar R, Li W, Bolla S, et al. Rhinovirus-Induced SIRT-1 via TLR2 Regulates Subsequent Type I and Type III IFN Responses in Airway Epithelial Cells. J Immunol. 2019;203:2508. doi:10.4049/jimmunol.1900165
- Somerville VS, Braakhuis AJ, Hopkins WG. Effect of Flavonoids on Upper Respiratory Tract Infections and Immune Function: A Systematic Review and Meta-Analysis. Adv Nutr. 2016;7:488. doi:10.3945/an.115.010538
- Song JH, Park KS, Kwon DH, Choi HJ. Anti-human rhinovirus 2 activity and mode of action of quercetin-7-glucoside from Lagerstroemia speciosa. J Med Food. 2013;16:274. doi:10.1089/jmf.2012.2290
- Ganesan S, Faris AN, Comstock AT, Wang Q, Nanua S, et al. Quercetin inhibits rhinovirus replication in vitro and in vivo. Antiviral Res. 2012;94:258. doi:10.1016/j.antiviral.2012.03.005
- Hemilä H, Chalker E. Vitamin C for the common cold and pneumonia. Pol Arch Intern Med. 2025;135. doi:10.20452/pamw.16926
- Hemilä H, Chalker E. Vitamin C reduces the severity of common colds: a meta-analysis. BMC Public Health. 2023;23:2468. doi:10.1186/s12889-023-17229-8
- Hemilä H, Chalker E. Bias against Vitamin C in Mainstream Medicine: Examples from Trials of Vitamin C for Infections. Life (Basel). 2022;12. doi:10.3390/life12010062
- Murni IK, Prawirohartono EP, Triasih R. Potential Role of Vitamins and Zinc on Acute Respiratory Infections Including Covid-19. Glob Pediatr Health. 2021;8:2333794X211021739. doi:10.1177/2333794X211021739
- Ran L, Zhao W, Wang H, Zhao Y, Bu H. Vitamin C as a Supplementary Therapy in Relieving Symptoms of the Common Cold: A Meta-Analysis of 10 Randomized Controlled Trials. Biomed Res Int. 2020;2020:8573742. doi:10.1155/2020/8573742
- Schloss J, Lauche R, Harnett J, Hannan N, Brown D, et al. Efficacy and safety of vitamin C in the management of acute respiratory infection and disease: A rapid review. Adv Integr Med. 2020;7:187. doi:10.1016/j.aimed.2020.07.008
- Kim TK, Lim HR, Byun JS. Vitamin C supplementation reduces the odds of developing a common cold in Republic of Korea Army recruits: randomised controlled trial. BMJ Mil Health. 2022;168:117. doi:10.1136/bmjmilitary-2019-001384
